The PKK has been fighting for an autonomous Kurdish region since the 1980s. The conflict has left tens of thousands of people dead.
Clashes between Turkish forces and PKK fighters have intensified in recent months.
Turkey refuses to recognize its Kurdish population as a distinct minority.
Turkish fighter jets have pounded at least 50 Kurdistan Workers’ Party’s (PKK) targets in northern Iraq.
"Sixteen F-16 fighter jets took off from their base in Diyarbakir in the southeast at around 20:00 GMT Tuesday and bombed the targets in Qandil Mountain in northern Iraq, 90 kilometers from the border," military sources said on Wednesday.
"More than 50 targets were hit in the three-hour operation," the statement added.
According to Abdulrazzaq Bayiz, mayor of Senkasar, the aircraft targeted two villages in the region, destroying a number of homes.
Turkish sources said that bunker-busters developed by Turkey's Scientific and Technological Research Council (TUBITAK) were used for the first time in the attacks on Tuesday.