Afghan riot police arrive to monitor the situation during an anti-US protest in Kabul on September 20, 2012.
Hundreds of anti-US protesters have blocked a main highway in the southern Afghanistan province of Zabul during a demonstration, Press TV report.
The protesters blocked the Kandahar-Kabul highway in the city of Qalat on Monday in response to a recent arrest and killing of two citizens of the province by US-led forces.
Foreign forces have reportedly refused to return the bodies of the victims to their families.
The Afghan protesters chanted slogans against the United States and foreign forces and demanded an end to such operations by foreign forces across the country.
Over Sunday and Monday, at least eight people were killed in US-led airstrikes in the Wardak and Kandahar provinces respectively situated in central and southern Afghanistan.
The loss of civilian lives at the hands of US-led foreign forces is a highly sensitive issue in Afghanistan, which has dramatically increased anti-American sentiment and triggered anti-US protests across the war-torn country.
The issue is also a major source of friction between Kabul and Washington.
The United States invaded Afghanistan in 2001 under the pretext of combating terrorism.
The offensive removed the Taliban from power, but insecurity continues to rise across Afghanistan, despite the presence of thousands of US-led troopers in the violence-scarred country.