Press TV reports.
The attack was carried out on Friday when the unmanned aerial vehicle fired missiles at an area near Gedo’s Dhobley town.
Authorities say dozens of people have been wounded in the airstrike.
The US military uses remote-controlled drones in Somalia for reconnaissance operations and targeted killings.
Washington has been carrying out assassination attacks using the unmanned aircraft in other countries including Afghanistan, Libya Pakistan, and Yemen.
The United States claims the CIA-run strikes are aimed at militants. But witness reports and figures offered by local authorities indicate the attacks have led to massive civilian deaths in these countries.
The UN has condemned the of US assassination drone strikes, saying they pose a challenge to international law.
A US assassination drone has pounded Somalia’s southwestern region of Gedo, killing at least 22 people in the attack,